Myeloid-Derived Suppressive Cells Deficient in Liver X Receptor α Protected From Autoimmune Hepatitis

Myeloid-Derived Suppressive Cells Deficient in Liver X Receptor α Protected From Autoimmune Hepatitis

Myeloid-derived suppressor cells (MDSCs) emerge as a promising candidate for the immunotherapy of autoimmune hepatitis (AIH). However, targets for modulating MDSC in AIH are still being searched. Liver X receptors (LXRs) are important nuclear receptors linking lipid metabolism and immune responses....

Full description

Bibliographic Details
Main Authors: Bo Li, Min Lian, Yikang Li, Qiwei Qian, Jun Zhang, Qiaoyan Liu, Ruqi Tang, Xiong Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
liver X receptor α
myeloid-derived suppressor cells
autoimmune hepatitis
interferon regulatory factor 8
immune-mediated hepatitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.732102/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.732102/full

Similar Items