Recruitment and activation of RSK2 by HIV-1 Tat.

The transcriptional activity of the integrated HIV provirus is dependent on the chromatin organization of the viral promoter and the transactivator Tat. Tat recruits the cellular pTEFb complex and interacts with several chromatin-modifying enzymes, including the histone acetyltransferases p300 and P...

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Bibliographic Details
Main Authors: Claudia Hetzer, Dwayne Bisgrove, Michael S Cohen, Angelika Pedal, Katrin Kaehlcke, Anja Speyerer, Kerstin Bartscherer, Jack Taunton, Melanie Ott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1764712?pdf=render