Single-Molecule Quantification of Translation-Dependent Association of mRNAs with the Endoplasmic Reticulum

Single-Molecule Quantification of Translation-Dependent Association of mRNAs with the Endoplasmic Reticulum

It is well established that mRNAs encoding secretory or membrane-bound proteins are translated on the surface of the endoplasmic reticulum (ER). The extent to which mRNAs that encode cytosolic proteins associate with the ER, however, remains controversial. To address this question, we quantified the...

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Bibliographic Details
Main Authors: Franka Voigt, Hui Zhang, Xianying A. Cui, Désirée Triebold, Ai Xin Liu, Jan Eglinger, Eliza S. Lee, Jeffrey A. Chao, Alexander F. Palazzo
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
endoplasmic reticulum
mRNA localization
translation
single-molecule
fluorescence microscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717318041

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http://www.sciencedirect.com/science/article/pii/S2211124717318041

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