Epigenetic changes of lentiviral transgenes in porcine stem cells derived from embryonic origin.

Because of the physiological and immunological similarities that exist between pigs and humans, porcine pluripotent cell lines have been identified as important candidates for preliminary studies on human disease as well as a source for generating transgenic animals. Therefore, the establishment and...

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Bibliographic Details
Main Authors: Kwang-Hwan Choi, Jin-Kyu Park, Hye-Sun Kim, Kyung-Jun Uh, Dong-Chan Son, Chang-Kyu Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747048?pdf=render