Resistance to enzymatic degradation and efficacy evaluation of crosslinked hyaluronic acid based commercial viscosupplements for knee osteoarthritis treatment

Resistance to enzymatic degradation and efficacy evaluation of crosslinked hyaluronic acid based commercial viscosupplements for knee osteoarthritis treatment

A significant number of people worldwide suffers from knee osteoarthritis (KOA), a chronic and painful disease that is linked to aging, traumatological events and sports medicine. Clinical research indicates that KOA exhibit an altered synovial fluid (SF) with lower endogenous hyaluronic acid (HA) c...

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Bibliographic Details
Main Authors: Jon Andrade del Olmo, Virginia Sáez Martínez, Nagore Martínez de Cestafe, José María Alonso, Claudia Goenaga Ibeas, Miguel Ucelay López de Heredia, Sandra Benito Cid, Raúl Pérez González
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Hyaluronic acid
Commercial injectable hydrogels
Viscosupplementation
Knee osteoarthritis
Traumatology
Sports medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893923001135

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http://www.sciencedirect.com/science/article/pii/S2666893923001135

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