Minocycline in phenotypic models of Huntington's disease

Minocycline in phenotypic models of Huntington's disease

Minocycline has been shown to be neuroprotective in various models of neurodegenerative diseases. However, its potential in Huntington's disease (HD) models characterized by calpain-dependent degeneration and inflammation has not been investigated. Here, we have tested minocycline in phenotypic...

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Bibliographic Details
Main Authors: Kadiombo Bantubungi, Carine Jacquard, Anita Greco, Annita Pintor, Abdelwahed Chtarto, Khalid Tai, Marie-Christine Galas, Liliane Tenenbaum, Nicole Déglon, Patrizia Popoli, Luisa Minghetti, Emmanuel Brouillet, Jacques Brotchi, Marc Levivier, Serge N. Schiffmann, David Blum
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Neurobiology of Disease
Subjects:
Huntington's disease
3-Nitropropionic acid
Quinolinic acid
Minocycline
Striatum
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002311

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http://www.sciencedirect.com/science/article/pii/S0969996104002311

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