Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery

Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery

Abstract Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis and represents one of the major challenges facing drug discovery initiatives worldwide. The considerable rise in bacterial drug resistance in recent years has led to the need of new drugs and drug regimens. Model systems a...

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Bibliographic Details
Main Authors: Amine Namouchi, Mena Cimino, Sandrine Favre-Rochex, Patricia Charles, Brigitte Gicquel
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Genomics
Subjects:
Drug discovery
Tuberculosis
Mycobacterium Aurum
Comparative genomics
Drug resistance
Whole genome sequencing
Online Access:http://link.springer.com/article/10.1186/s12864-017-3924-y

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http://link.springer.com/article/10.1186/s12864-017-3924-y

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