Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.

Current pathological diagnostics include the analysis of (epi-)genetic alterations as well as oncogenic pathways. Deregulated mammalian target of rapamycin complex 1 (mTORC1) signaling has been implicated in a variety of cancers including malignant gliomas and is considered a promising target in can...

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Main Authors: Patrick N Harter, Lukas Jennewein, Peter Baumgarten, Elena Ilina, Michael C Burger, Anna-Luisa Thiepold, Julia Tichy, Martin Zörnig, Christian Senft, Joachim P Steinbach, Michel Mittelbronn, Michael W Ronellenfitsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4437987?pdf=render

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http://europepmc.org/articles/PMC4437987?pdf=render

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