Developmental Changes in Hepatic Antioxidant Capacity Are Age- and Sex-Dependent

Developmental inadequacy in hepatic antioxidant defenses may contribute to chemical toxicity and pediatric liver diseases. We measured a comprehensive panel of antioxidants in liver tissue from 27 normal pediatric donors. Glutathione reductase declined with age (P = 0.008, r = −0.54, Spearman) while...

Full description

Bibliographic Details
Main Authors: Shogo J. Miyagi, Isaac W. Brown, Jessica M-L. Chock, Abby C. Collier
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319310801