Design, synthesis, biological evaluation and molecular docking study of novel pleuromutilin derivatives containing substituted benzoxazole as antibacterial agents

A series of pleuromutilin analogs containing substituted benzoxazole were designed, synthesised, and assessed for their antibacterial activity both in vivo and in vitro. The MIC of the synthesised derivatives was initially assessed using the broth dilution method against four strains of Staphylococc...

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Detaylı Bibliyografya
Asıl Yazarlar: Jie Ren, Qi-Wen Zhang, Xian-Jin He, Xiao-Ying Chen, Zi-Dan Zhou, Zhen-Ling Zeng, Zhen Jin, You-Zhi Tang
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Taylor & Francis Group 2023-12-01
Seri Bilgileri:Journal of Enzyme Inhibition and Medicinal Chemistry
Konular:
Online Erişim:https://www.tandfonline.com/doi/10.1080/14756366.2023.2251712