Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of −1 Frameshifting by tRNA<sup>Ser3</sup>

In-frame decoding in the ribosome occurs through canonical or wobble Watson&#8722;Crick pairing of three mRNA codon bases (a triplet) with a triplet of anticodon bases in tRNA. Departures from the triplet&#8722;triplet interaction can result in frameshifting, meaning downstream mRNA codons a...

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Bibliographic Details
Main Authors: Thomas Caulfield, Matt Coban, Alex Tek, Samuel Coulbourn Flores
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/11/745