Tocilizumab reduces the unmanageable inflammatory reaction of a patient with Aicardi-Goutières syndrome type 7 during treatment with ruxolitinib

Tocilizumab reduces the unmanageable inflammatory reaction of a patient with Aicardi-Goutières syndrome type 7 during treatment with ruxolitinib

Abstract Background Aicardi-Goutières syndrome (AGS) is a rare hereditary early-onset encephalopathy characterized by upregulation of the type I interferon pathway, poorly responsive to conventional immunosuppression. Case presentation We describe a 7-year-old Chinese boy who developed symptoms at t...

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Bibliographic Details
Main Authors: Wei Wang, Siming Peng, Sihao Gao, Meiying Quan, Lijuan Gou, Changyan Wang, Zhixing Sun, Zhuo Li, Dongmei Lian, Hongmei Song
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Aicardi-Goutières syndrome
Treatment
Online Access:https://doi.org/10.1186/s12969-023-00899-4

Internet

https://doi.org/10.1186/s12969-023-00899-4

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