Inhibitory effect of tetrahydrocurcumin on dimethylnitrosamine-induced liver fibrosis in rats

Inhibitory effect of tetrahydrocurcumin on dimethylnitrosamine-induced liver fibrosis in rats

Chronic liver disease is characterized by an exacerbated accumulation of deposition of collagen, causing progressive fibrosis, which may lead to cirrhosis. We evaluated the inhibitory effect of tetrahydrocurcumin (THC), a major metabolite of curcumin, on liver fibrogenesis both in vitro, HSC-T6 cell...

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Bibliographic Details
Main Authors: Monthana Weerawatanakorn, Shu-Chen Hsieh, Mei-Ling Tsai, Ching-Shu Lai, Li-Mei Wu, Vladimir Badmaev, Chi-Tang Ho, Min-Hsiung Pan
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Functional Foods
Subjects:
THC
Dimethylnitrosamine
Hepatic stellate cells
Liver fibrosis
Smooth muscle actin
TGF-β1
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614000474

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http://www.sciencedirect.com/science/article/pii/S1756464614000474

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