Genetic framework of type 2 diabetes mellitus

More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.

Bibliographic Details
Main Authors: Irina Arkad'evna Bondar', Olesya Yur'evna Shabel'nikova
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-12-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/3847