Genetic framework of type 2 diabetes mellitus
More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2013-12-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/3847 |
| _version_ | 1797255227860058112 |
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| author | Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova |
| author_facet | Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova |
| author_sort | Irina Arkad'evna Bondar' |
| collection | DOAJ |
| description | More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely. |
| first_indexed | 2024-03-08T15:21:33Z |
| format | Article |
| id | doaj.art-9d5d5da8687a41c0a2fabd1e00a23ebe |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:02:30Z |
| publishDate | 2013-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-9d5d5da8687a41c0a2fabd1e00a23ebe2024-03-20T11:47:58ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782013-12-01164111610.14341/DM2013411-163817Genetic framework of type 2 diabetes mellitusIrina Arkad'evna Bondar'0Olesya Yur'evna Shabel'nikova1Novosibirsk State Medical University, NovosibirskNovosibirsk State Regional Hospital, NovosibirskMore than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.https://www.dia-endojournals.ru/jour/article/view/3847type 2 diabetes mellitusgeneticsbeta-cell dysfunctioninsulin resistance |
| spellingShingle | Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova Genetic framework of type 2 diabetes mellitus Сахарный диабет type 2 diabetes mellitus genetics beta-cell dysfunction insulin resistance |
| title | Genetic framework of type 2 diabetes mellitus |
| title_full | Genetic framework of type 2 diabetes mellitus |
| title_fullStr | Genetic framework of type 2 diabetes mellitus |
| title_full_unstemmed | Genetic framework of type 2 diabetes mellitus |
| title_short | Genetic framework of type 2 diabetes mellitus |
| title_sort | genetic framework of type 2 diabetes mellitus |
| topic | type 2 diabetes mellitus genetics beta-cell dysfunction insulin resistance |
| url | https://www.dia-endojournals.ru/jour/article/view/3847 |
| work_keys_str_mv | AT irinaarkadevnabondar geneticframeworkoftype2diabetesmellitus AT olesyayurevnashabelnikova geneticframeworkoftype2diabetesmellitus |