Plasma extracellular vesicles bearing PD-L1, CD40, CD40L or TNF-RII are significantly reduced after treatment of AIDS-NHL

Abstract Emerging evidence shows that tumor cells secrete extracellular vesicles (EVs) that carry bioactive cell surface markers, such as programmed death-ligand 1 (PD-L1), which can modulate immune responses and inhibit anti-tumor responses, potentially playing a role in lymphomagenesis and in prom...

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Bibliographic Details
Main Authors: Laura E. Martínez, Shelly Lensing, Di Chang, Larry I. Magpantay, Ronald Mitsuyasu, Richard F. Ambinder, Joseph A. Sparano, Otoniel Martínez-Maza, Marta Epeldegui
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13101-8