Osteosarcoma cells can reproduce into tumorigenic cells by escaping chemotherapy-induced cell senescence
Objective To explore whether osteosarcoma cells can escape from cell senescence and reproduce, and to evaluate the oncogenic ability of senescent-escaped cells. To explain the mechanism of osteosarcoma recurrence from a new perspective. Methods Doxorubicin (DOX) was used to develop aging model of U2...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2020-02-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190003.pdf |