Effect of nocturnal EPAP titration to abolish tidal expiratory flow limitation in COPD patients with chronic hypercapnia: a randomized, cross-over pilot study

Abstract Background Tidal expiratory flow limitation (EFLT) promotes intrinsic PEEP (PEEPi) in patients with chronic obstructive pulmonary disease (COPD). Applying non-invasive ventilation (NIV) with an expiratory positive airway pressure (EPAP) matching PEEPi improves gas exchange, reduces work of...

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Bibliographic Details
Main Authors: Emanuela Zannin, Ilaria Milesi, Roberto Porta, Simona Cacciatore, Luca Barbano, R. Trentin, Francesco Fanfulla, Michele Vitacca, Raffaele L. Dellacà
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-020-01567-x