A preclinical model of THC edibles that produces high-dose cannabimimetic responses

A preclinical model of THC edibles that produces high-dose cannabimimetic responses

No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ9-tetrahydrocannabinol (THC) and its intoxicating effects, mainly owing to the aversive response of rodents to THC that limits intake. Here, we developed a palatable THC formulation and an opt...

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Bibliographic Details
Main Authors: Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Veronica Elizabeth Slaven, Daniele Piomelli, Michael R Bruchas, Nephi Stella, Benjamin Bruce Land
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
cannabinoids
behavior
route of administration
Online Access:https://elifesciences.org/articles/89867

Internet

https://elifesciences.org/articles/89867

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