Porcine foetal and neonatal CYP3A liver expression

Human cytochrome P450 3A7 (CYP3A7) and cytochrome P450 3A4 (CYP3A4) are hepatic metabolising enzymes which participates in the biotransformation of endo- and exogenous substances in foetuses and neonates respectively. These CYP3A enzymes display an inverse relationship: CYP3A7 is the dominant enzyme...

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Bibliographic Details
Main Authors: Marie Louise Hiort Hermann, Mette Tingleff Skaanild
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Journal of Xenobiotics
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/xeno/article/view/15