Sequential adaptive mutations enhance efficient vector switching by Chikungunya virus and its epidemic emergence.

The adaptation of Chikungunya virus (CHIKV) to a new vector, the Aedes albopictus mosquito, is a major factor contributing to its ongoing re-emergence in a series of large-scale epidemics of arthritic disease in many parts of the world since 2004. Although the initial step of CHIKV adaptation to A....

Full description

Bibliographic Details
Main Authors: Konstantin A Tsetsarkin, Scott C Weaver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3234230?pdf=render