Analysis of the p53 gene by PCR-SSCP in ten cases of Wilms’ tumor

CONTEXT: Mutations of the p53 tumor suppressor gene are the most frequent alterations observed in human neoplasias affecting adults. In pediatric oncology, however, they have seldom been identified. Wilms’ tumor is a renal neoplasia commonly occurring in children and is associated with mutations of...

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Bibliographic Details
Main Authors: Ricardo Defavery, José Alexandre Rodrigues Lemos, Simone Kashima, José Eduardo Bernardes, Carlos Alberto Scridelli, Dimas Tadeu Covas, Luiz Gonzaga Tone
Format: Article
Language:English
Published: Associação Paulista de Medicina 2000-03-01
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802000000200005&lng=en&tlng=en