Live imaging of delamination in Drosophila shows epithelial cell motility and invasiveness are independently regulated

Abstract Delaminating cells undergo complex, precisely regulated changes in cell–cell adhesion, motility, polarity, invasiveness, and other cellular properties. Delamination occurs during development and in pathogenic conditions such as cancer metastasis. We analyzed the requirements for epithelial...

Full description

Bibliographic Details
Main Authors: Mikiko Inaki, Smitha Vishnu, Kenji Matsuno
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20492-1