Premorbid performances determine the deleterious effects of nigrostriatal degeneration and pramipexole on behavioural flexibility
Abstract Subtle cognitive impairment can occur early in the course of Parkinson’s disease (PD) and may manifest under different forms of executive dysfunction such as impaired cognitive flexibility. The precise contribution of nigrostriatal dopaminergic neurodegeneration to these non-motor features...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-023-00475-3 |