Leaf-venation-directed cellular alignment for macroscale cardiac constructs with tissue-like functionalities
Abstract Recapitulating the complex structural, mechanical, and electrophysiological properties of native myocardium is crucial to engineering functional cardiac tissues. Here, we report a leaf-venation-directed strategy that enables the compaction and remodeling of cell-hydrogel hybrids into highly...
Main Authors: | Mao Mao, Xiaoli Qu, Yabo Zhang, Bingsong Gu, Chen Li, Rongzhi Liu, Xiao Li, Hui Zhu, Jiankang He, Dichen Li |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-37716-1 |
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