Ribosylation induced structural changes in Bovine Serum Albumin: understanding high dietary sugar induced protein aggregation and amyloid formation

Non-enzymatic glycation of proteins is believed to be the root cause of high dietary sugar associated pathophysiological maladies. We investigated the structural changes in protein during progression of glycation using ribosylated Bovine Serum Albumin (BSA). Non enzymatic attachment of about 45 ribo...

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Bibliographic Details
Main Authors: Ahana Das, Pijush Basak, Arnab Pramanik, Rajib Majumder, Avishek Ghosh, Saugata Hazra, Manas Guria, Maitree Bhattacharyya, Samudra Prosad Banik
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402031896X