Extensive downregulation of immune gene expression by microRNA-140-3p 5′ isomiR in an in vitro model of osteoarthritis
Objective: MicroRNA-140-3p is the most prevalent form of canonical miR-140 in native chondrocytes. IsomiRs are sequence variants of microRNAs with potentially distinct functionalities. Here we present functional studies of canonical microRNA-140-3p and two of its most prevalent isomiRs, a 5′ isomiR...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Osteoarthritis and Cartilage Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665913121000522 |