In Vitro Characterization of the Human Skeletal Stem Cell-like Properties of Primary Bone-Derived Mesenchymal Stem/Stromal Cells in Patients with Late and Early Hip Osteoarthritis

In Vitro Characterization of the Human Skeletal Stem Cell-like Properties of Primary Bone-Derived Mesenchymal Stem/Stromal Cells in Patients with Late and Early Hip Osteoarthritis

Human skeletal stem cells (hSSCs) were recently identified as podoplanin (PDPN)/CD73/CD164-positive and CD146-negative cells that decline with age, and play a role in the pathogenesis of osteoarthritis (OA). The aim of this study was to identify the hSSC-like properties of bone-derived mesenchymal s...

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Bibliographic Details
Main Authors: Lara Jasenc, Klemen Stražar, Anže Mihelič, Rene Mihalič, Rihard Trebše, Gregor Haring, Matjaž Jeras, Janja Zupan
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
human skeletal stem cells (hSSCs)
late osteoarthritis (OA)
early OA
bone-derived mesenchymal stem/stromal cells (MSCs)
podoplanin (PDPN)
CD73
Online Access:https://www.mdpi.com/2075-1729/12/6/899

Internet

https://www.mdpi.com/2075-1729/12/6/899

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