Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis.

BACKGROUND: Gene expression analysis in Leishmania donovani (Ld) identified an orthologue of the urea cycle enzyme, argininosuccinate synthase (LdASS), that was more abundantly expressed in amastigotes than in promastigotes. In order to characterize in detail this newly identified protein in Leishma...

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Bibliographic Details
Main Authors: Ines Lakhal-Naouar, Armando Jardim, Rona Strasser, Shen Luo, Yukiko Kozakai, Hira L Nakhasi, Robert C Duncan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3475689?pdf=render