Two-stage genome-wide search for epistasis with implementation to Recombinant Inbred Lines (RIL) populations.

OBJECTIVE AND METHODS:This paper proposes an inegrative two-stage genome-wide search for pairwise epistasis on expression quantitative trait loci (eQTL). The traits are clustered into multi-trait complexes that account for correlations between them that may result from common epistasis effects. The...

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Bibliographic Details
Main Authors: Pavel Goldstein, Abraham B Korol, Anat Reiner-Benaim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275240?pdf=render