A single-center, randomized, parallel design study to evaluate the efficacy of donepezil in improving visuospatial abilities in patients with mild cognitive impairment using eye-tracker: the COG-EYE study protocol for a phase II trial

A single-center, randomized, parallel design study to evaluate the efficacy of donepezil in improving visuospatial abilities in patients with mild cognitive impairment using eye-tracker: the COG-EYE study protocol for a phase II trial

Abstract Background Cholinesterase inhibitors (ChEIs) decrease long-term cognitive decline in patients with Alzheimer’s disease (AD); however, there is little evidence that ChEIs affect cognitive test scores in patients with mild cognitive impairment (MCI). Conventional endpoints, such as cognitive...

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Bibliographic Details
Main Authors: Ko Woon Kim, Qi Wang, Se Hee Koo, Byoung-Soo Shin
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Trials
Subjects:
Mild cognitive impairment
Donepezil
Cholinesterase inhibitors
Visuospatial dysfunction
Eye-tracking
Digital pen
Online Access:https://doi.org/10.1186/s13063-022-06781-0

Internet

https://doi.org/10.1186/s13063-022-06781-0

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