A lncRNA-encoded mitochondrial micropeptide exacerbates microglia-mediated neuroinflammation in retinal ischemia/reperfusion injury

Abstract As a common pathology of many ocular disorders such as diabetic retinopathy and glaucoma, retinal ischemia/reperfusion (IR) triggers inflammation and microglia activation that lead to irreversible retinal damage. The detailed molecular mechanism underlying retinal IR injury, however, remain...

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Bibliographic Details
Main Authors: Xintong Zheng, Mingwei Wang, Shuting Liu, Haiqiao Chen, Yifei Li, Fa Yuan, Ludong Yang, Suo Qiu, Hongwei Wang, Zhi Xie, Mengqing Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05617-2