Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

Autophagy is a major pathway for the clearance of harmful material from the cytoplasm. During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles called autophagosomes. Autophagosomes form in a de novo manner and, in the course of their formation, isolate cargo mater...

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Bibliographic Details
Main Authors: Bettina Wurzer, Gabriele Zaffagnini, Dorotea Fracchiolla, Eleonora Turco, Christine Abert, Julia Romanov, Sascha Martens
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
selective autophagy
cargo receptor
in vitro reconstitution
Online Access:https://elifesciences.org/articles/08941

Internet

https://elifesciences.org/articles/08941

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