Axonal energy metabolism, and the effects in aging and neurodegenerative diseases

Abstract Human studies consistently identify bioenergetic maladaptations in brains upon aging and neurodegenerative disorders of aging (NDAs), such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and Amyotrophic lateral sclerosis. Glucose is the major brain fuel and glucose hypome...

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Bibliographic Details
Main Authors: Sen Yang, Jung Hyun Park, Hui-Chen Lu
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-023-00634-3