Post-Translational Regulation of ARF: Perspective in Cancer

Post-Translational Regulation of ARF: Perspective in Cancer

Tumorigenesis can be induced by various stresses that cause aberrant DNA mutations and unhindered cell proliferation. Under such conditions, normal cells autonomously induce defense mechanisms, thereby stimulating tumor suppressor activation. ARF, encoded by the <i>CDKN2a</i> locus, is o...

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Bibliographic Details
Main Authors: Jinho Seo, Daehyeon Seong, Seung Ri Lee, Doo-Byoung Oh, Jaewhan Song
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
ARF
post-translational modification
transcriptional regulation
tumor suppressor
cancer
p14
Online Access:https://www.mdpi.com/2218-273X/10/8/1143

Internet

https://www.mdpi.com/2218-273X/10/8/1143

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