Quantification of unintegrated HIV-1 DNA at the single cell level in vivo.

In the nucleus of HIV-1 infected cells, unintegrated HIV-1 DNA molecules exist in the form of one and two LTR circles and linear molecules with degraded extremities. In tissue culture they are invariably more numerous than the provirus, the relative proportion of integrated to unintegrated forms var...

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Bibliographic Details
Main Authors: Rodolphe Suspène, Andreas Meyerhans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344866?pdf=render