Low-dose pleiotropic radiosensitive nanoformulations for three-pronged radiochemotherapy of hypoxic brain glioblastoma under BOLD/DWI monitoring

Low-dose pleiotropic radiosensitive nanoformulations for three-pronged radiochemotherapy of hypoxic brain glioblastoma under BOLD/DWI monitoring

Abstract Background Hypoxia-mediated radioresistance is the main obstacle to the successful treatment of glioblastoma (GBM). Enhancing hypoxic radiosensitivity and alleviating tumor hypoxia are both effective means to improve therapeutic efficacy, and the combination of the two is highly desirable a...

Full description

Bibliographic Details
Main Authors: Fangshi Zhao, Xiaoyi Wang, Wei Zhu, Dongju Zhao, Caihua Ye, Yanyan Guo, Yan Dou
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Nanotechnology
Subjects:
Nanomedicine
Glioblastoma
Tumor hypoxia
Radiochemotherapy
Hypoxia-activated therapy
Nitric oxide
Online Access:https://doi.org/10.1186/s12645-023-00159-w

Internet

https://doi.org/10.1186/s12645-023-00159-w

Similar Items