Enhancer-associated regulatory network and gene signature based on transcriptome and methylation data to predict the survival of patients with lung adenocarcinoma

Enhancer-associated regulatory network and gene signature based on transcriptome and methylation data to predict the survival of patients with lung adenocarcinoma

Accumulating evidence has proved that aberrant methylation of enhancers plays regulatory roles in gene expression for various cancers including lung adenocarcinoma (LUAD). In this study, the transcriptome and methylation data of The Cancer Genome Atlas (TCGA)-LUAD cohort were comprehensively analyze...

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Bibliographic Details
Main Authors: Shihao Huang, Shiyu Chen, Di Zhang, Jiamei Gao, Linhua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
lung adenocarcinoma
enhancer
methylation
regulatory network
gene signature
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1008602/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1008602/full

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