SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

Objective: Mitochondrial “retrograde” signaling may stimulate organelle biogenesis as a compensatory adaptation to aberrant activity of the oxidative phosphorylation (OXPHOS) system. To maintain energy-consuming processes in OXPHOS deficient cells, alternative metabolic pathways are functionally cou...

Full description

Bibliographic Details
Main Authors: Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, Debora Gentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, Kristian Händler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, Daniele Bano
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Molecular Metabolism
Subjects:
Autophagy
Caenorhabditis elegans
Longevity
MICU1
Mitochondria
Sphingosine signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000722

Internet

http://www.sciencedirect.com/science/article/pii/S2212877822000722

Similar Items