Influenza virus A/Beijing/501/2009(H1N1) NS1 interacts with β-tubulin and induces disruption of the microtubule network and apoptosis on A549 cells.

NS1 of influenza A virus is a key multifunctional protein that plays various roles in regulating viral replication mechanisms, host innate/adaptive immune responses, and cellular signalling pathways. These functions rely on its ability to participate in a multitude of protein-protein and protein-RNA...

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Bibliographic Details
Main Authors: Xueqing Han, Zhihui Li, Hongjun Chen, Huiyu Wang, Lin Mei, Shaoqiang Wu, Tianyi Zhang, Bohua Liu, Xiangmei Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3491056?pdf=render