Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

The goal of this study was to analyze whether mitochondria-associated endoplasmic reticulum membrane (MAMs) dysfunction mediated arsenic (As)-evoked pulmonary ferroptosis and acute lung injury (ALI). As exposure led to alveolar structure damage, inflammatory cell infiltration and pulmonary function...

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Bibliographic Details
Main Authors: Meng-Die Li, Lin Fu, Bian-Bian Lv, Ying Xiang, Hui-Xian Xiang, De-Xiang Xu, Hui Zhao
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Arsenic
Ferroptosis
PERK
Mitofusin-2
MtROS
Acute lung injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322004353

Internet

http://www.sciencedirect.com/science/article/pii/S0147651322004353

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