In vitro skin culture media influence the viability and inflammatory response of primary macrophages

Abstract The replacement of animal models for investigation of inflammation and wound healing has been advancing by means of in vitro skin equivalents with increasing levels of complexity. However, the current in vitro skin models still have a limited pre-clinical relevance due to their lack of immu...

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Bibliographic Details
Main Authors: Chiara Griffoni, Berna Neidhart, Ke Yang, Florian Groeber-Becker, Katharina Maniura-Weber, Thomas Dandekar, Heike Walles, Markus Rottmar
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86486-7