N-methyl-D-aspartate receptor hypofunction as a potential contributor to the progression and manifestation of many neurological disorders

N-methyl-D-aspartate receptor hypofunction as a potential contributor to the progression and manifestation of many neurological disorders

N-methyl-D-aspartate receptors (NMDA) are glutamate-gated ion channels critical for synaptic transmission and plasticity. A slight variation of NMDAR expression and function can result in devastating consequences, and both hyperactivation and hypoactivation of NMDARs are detrimental to neural functi...

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Bibliographic Details
Main Authors: Bin Dong, Yang Yue, Han Dong, Yuehui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
N-methyl-D-aspartate (NMDA) receptors
schizophrenia
GRIN related disease
NMDAR antibody encephalitis
age-related cognitive decline
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1174738/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1174738/full

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