An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

Marrow niches in osteosarcoma (OS) are a specialized microenvironment that is essential for the maintenance and regulation of OS cells. However, existing animal xenograft models are plagued by variability, complexity, and high cost. Herein, we used a decellularized osteosarcoma extracellular matrix...

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Bibliographic Details
Main Authors: Zuyan Lu, XiangWan Miao, Chenyu Zhang, Binbin Sun, Aleksander Skardal, Anthony Atala, Songtao Ai, JiaNing Gong, Yongqiang Hao, Jie Zhao, Kerong Dai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-04-01
Series:Bioactive Materials
Subjects:
3D printing
Osteosarcoma-on-a-chip
Organ-on-a-chip
Bone marrow niches
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23004012

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http://www.sciencedirect.com/science/article/pii/S2452199X23004012

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