Phosphate Precipitates and Water-Soluble Aggregates in Re-analyzed Solubility-pH Data of Twenty-five Basic Drugs
The purpose of the study was to assess the stoichiometries of phosphate precipitates and determine the intrinsic solubilities, S0, of 25 basic drugs from their published solubility-pH profiles in the landmark study of Bergström et al. (2004), where 0.15 M phosphate buffer media had been used. A sec...
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Format: | Article |
Language: | English |
Published: |
International Association of Physical Chemists (IAPC)
2014-04-01
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Series: | ADMET and DMPK |
Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/31 |