Mycobacterial-specific secretion of cytokines and chemokines in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis

Mycobacterial-specific secretion of cytokines and chemokines in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis

BackgroundCurrently, diagnosis of latent TB infection (LTBI) is based on the secretion of IFN-γ in response to Mycobacterium tuberculosis (Mtb) antigens, the absence of which is regarded as no infection. Some individuals appear to resist Mtb infection despite sustained exposure (resisters). In this...

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Bibliographic Details
Main Authors: Muki Shehu Shey, Avuyonke Balfour, Nomawethu Masina, Abulele Bekiswa, Charlotte Schutz, Rene Goliath, Rachel Dielle, Patrick DMC. Katoto, Katalin Andrea Wilkinson, David Lewinsohn, Deborah Anne Lewinsohn, Graeme Meintjes
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
latent TB infection (LTBI)
resister
cytokines
chemokines
Mycobacterium tuberculosis
antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176615/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176615/full

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