Biological clock gene PER1 regulates circadian rhythms of BAX, BCL2 and PCNA expression in oral squamous carcinoma cells

Objective To explore the regulative role of biological clock gene PER1 in the circadian rhythms of proliferation, apoptosis and expression of intracellular BAX, BCL2 and PCNA in oral squamous carcinoma cells (OSCC). Methods The SCC15 cells stably overexpressing PER1 gene (OE-PER1-SCC15) and negative...

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Bibliographic Details
Main Authors: YIN Shilin, ZHANG Zhiwei, TANG Hong, YANG Kai
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2022-08-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202202015.htm