High expression of interleukine-1 receptor antagonist in rheumatoid arthritis: Association with IL1RN*2/2 genotype

High expression of interleukine-1 receptor antagonist in rheumatoid arthritis: Association with IL1RN*2/2 genotype

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and pro-inflammatory cytokines production. IL-1Ra is an anti-inflammatory cytokine codified by IL1RN gene that blocks IL-1 signalling. A VNTR polymorphism of 86 bp in IL1RN gene has been associated with RA risk and regu...

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Bibliographic Details
Main Authors: S. Ramírez-Pérez, U. De la Cruz-Mosso, J. Hernández-Bello, G. E. Martínez-Bonilla, M. G. Ramírez-Dueñas, A. L. Pereira-Suárez, I. Parra Rojas, E. Martínez-López, J. Macías-Barragán, J. F. Muñoz-Valle
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:Autoimmunity
Subjects:
il-1ra
rheumatoid arthritis
expression
il1rn vntr
polymorphism
Online Access:http://dx.doi.org/10.1080/08916934.2017.1412431

Internet

http://dx.doi.org/10.1080/08916934.2017.1412431

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