Plasma cell infiltration and treatment effect in breast cancer patients treated with neoadjuvant chemotherapy

Plasma cell infiltration and treatment effect in breast cancer patients treated with neoadjuvant chemotherapy

Abstract Background Tumour-infiltrating lymphocyte (TIL)-high breast tumours have a high rate of pathological complete response (pCR) with neoadjuvant chemotherapy. In our routine pathological diagnoses of biopsy specimens from pCR cases, we have observed a high infiltration of plasma cells (PCs). A...

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Bibliographic Details
Main Authors: Asumi Sakaguchi, Yoshiya Horimoto, Hiroko Onagi, Daiki Ikarashi, Takayuki Nakayama, Tetsuya Nakatsura, Hideo Shimizu, Kuniaki Kojima, Takashi Yao, Toshiharu Matsumoto, Kanako Ogura, Shigehisa Kitano
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Plasma cell
Tumour-infiltrating lymphocyte
Neoadjuvant chemotherapy
Local immune microenvironment
Multiplexed fluorescent immunohistochemistry
Online Access:https://doi.org/10.1186/s13058-021-01477-w

Internet

https://doi.org/10.1186/s13058-021-01477-w

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