Plasma cell infiltration and treatment effect in breast cancer patients treated with neoadjuvant chemotherapy

Plasma cell infiltration and treatment effect in breast cancer patients treated with neoadjuvant chemotherapy

Abstract Background Tumour-infiltrating lymphocyte (TIL)-high breast tumours have a high rate of pathological complete response (pCR) with neoadjuvant chemotherapy. In our routine pathological diagnoses of biopsy specimens from pCR cases, we have observed a high infiltration of plasma cells (PCs). A...

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Bibliographic Details
Main Authors:	Asumi Sakaguchi, Yoshiya Horimoto, Hiroko Onagi, Daiki Ikarashi, Takayuki Nakayama, Tetsuya Nakatsura, Hideo Shimizu, Kuniaki Kojima, Takashi Yao, Toshiharu Matsumoto, Kanako Ogura, Shigehisa Kitano
Format:	Article
Language:	English
Published:	BMC 2021-10-01
Series:	Breast Cancer Research
Subjects:	Breast cancer Plasma cell Tumour-infiltrating lymphocyte Neoadjuvant chemotherapy Local immune microenvironment Multiplexed fluorescent immunohistochemistry
Online Access:	https://doi.org/10.1186/s13058-021-01477-w

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